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Celebrex (celecoxib) is chemically designated as (4-methylphenyl), (trifluoromethyl)benzenesulfonamide and is a diaryl-substituted pyrazole.
Celebrex oral capsules contain either 50 mg, 100 mg, 200 mg or 400 mg tablet, together with inactive ingredients including: gelatin, croscarmellose sodium, edible inks, lactose monohydrate, magnesium stearate, povidone and sodium lauryl sulfate.
Carefully consider the benefits and risks of Celebrex and other treatment options before deciding to use Celebrex. Celebrex is indicated for relief of the signs and symptoms of Osteoarthritis, rheumatoid arthritis, JRA in patients 2 years and older.
Celebrex is indicated to reduce the number of adenomatous colorectal polyps in FAP patients. It is not known whether there is a clinical benefit from a decreasing number of colorectal polyps in FAP patients. It is also not known whether the effects of this drug will persist after Celebrex is discontinued. The effectivity and safety of Celebrex treatment in patients with FAP beyond six months have not been studied.
Celebrex can be taken with or without meal. This drug is also indicated for relief of the signs and symptoms of OA the recommended oral dose is 200 mg per day administered as a single dose or as 100 mg twice daily.
It can be also be used for relief of the signs and symptoms of RA the recommended oral dose is 100 to 200 mg twice daily. It may be used also for the relief of the signs and symptoms of JRA the recommended oral dose for pediatric patients (age 2 years and older) is based on weight.
For patients who have difficulty swallowing capsules, the contents of the capsule can be added to applesauce. The entire capsule contents are carefully emptied onto a level teaspoon of cool/ room temperature applesauce and ingested immediately with water. The sprinkled capsule contents on applesauce are stable for up to 6 hours under refrigerated conditions at recommended temperature.
It can be also be used for the management of the signs and symptoms of AS, the recommended dose of Celebrex is 200 mg daily in single (once per day) or divided (twice per day) doses.